- Sandwich Shop Restaurants, Franklinton
- Sawmill & Planing Mills, Franklinton
- Sawmill Supplies & Equipment Repair, Franklinton
- Sawmill, Paper & Woodworking Supplies, Machinery & Equipment, Franklinton
- Scrap & Waste Materials, Franklinton
- Screen Printing, Franklinton
- Secondary Schools, Franklinton
- Senior Citizens Information & Services, Franklinton
- Senior Citizens Service & Health Organizations, Franklinton
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- Septic Tank Pumping & Cleaning, Franklinton - Septic Systems
- Shopping & Shopping Services, Franklinton
- Social Services & Welfare, Franklinton
- Societies & Foundation Associations, Franklinton
- Specialty Animal Services, Franklinton
- State Government, Franklinton
- Stone & Rock Quarry, Franklinton - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
- Surveyor Services, Franklinton - Surveying Service
- Surveyors, Franklinton
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