- Obstetricians & Gynecologists, Matthews - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Off Road Vehicles, Matthews
- Off Road Vehicles Parts & Accessories, Matthews
- Office Supplies, Equipment & Office Furniture Stores, Matthews
- Oil & Gas Additives & Supplies, Matthews
- Oil & Gas Companies, Matthews
- Oil & Petroleum Products, Matthews - Merchant, Wholesalers, etc
- Oil Change & Lubrication, Matthews - Auto Oil & Quick Lube
- Oilfield Trucking, Matthews
- Oncologists, Matthews - Cancer Doctors, Physicians & Surgeons (Oncology)
- Ophthalmologists, Matthews - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Matthews
- Opticians, Matthews
- Optometrists, Matthews - Eye Doctors, Physicians & Surgeons (Optometry)
- Optometry Clinics, Matthews - Eye Clinics
- Oral Surgeon, Matthews - Dentists - Oral & Maxillofacial Surgeons
- Organ Donation & Tissue Banks, Matthews
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- Organizing Services & Products – Household & Business, Matthews
- Oriental Goods & Products Stores, Matthews
- Ornamental Greenhouses, Matthews
- Ornamental Nursery, Matthews
- Ornamental Nursery Services, Matthews
- Orthodontist, Matthews - Teeth Straightening, Invisalign & Dental Braces
- Orthodox Churches, Matthews
- Orthopedic Shoes, Matthews
- Orthopedists, Matthews - Orthopedic Surgery Doctors, Physicians & Surgeons
- Orthotics and Prosthetics, Matthews
- Other Building Materials & Supplies, Matthews
- Other Lodging, Matthews
- Outdoor & Lawn & Garden Equipment Repair & Service, Matthews
- Outdoor Advertising & Billboard, Matthews
- Outdoor Equipment & Accessories, Matthews
- Overhead Door, Matthews
- Oxygen & Respiratory Equipment & Supplies, Matthews - Oxygen Concentrator, Tank, Machine, etc
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