- Obstetricians, Mooresville - Obstetrics and Gynecology Doctors, Physicians & Surgeons
- Obstetricians & Gynecologists, Mooresville - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Occupational Health Care Professionals, Mooresville
- Occupational Therapy, Mooresville - Occupational Health Specialists
- Off Road Vehicles, Mooresville
- Off Road Vehicles Parts & Accessories, Mooresville
- Office Supplies, Equipment & Office Furniture Stores, Mooresville
- Oil & Grease Seals, Mooresville
- Oil Change & Lubrication, Mooresville - Auto Oil & Quick Lube
- Oil Extraction Downhole, Mooresville
- Oil Industry & Oil Field Equipment & Services, Mooresville - Oil Companies
- Old Age Homes Service, Mooresville
- Oncologists, Mooresville - Cancer Doctors, Physicians & Surgeons (Oncology)
- Ophthalmologists, Mooresville - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Mooresville
- Opticians, Mooresville
- Optometrists, Mooresville - Eye Doctors, Physicians & Surgeons (Optometry)
- Oral Surgeon, Mooresville - Dentists - Oral & Maxillofacial Surgeons
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- Ornamental Nursery, Mooresville
- Ornamental Nursery Services, Mooresville
- Orthodontist, Mooresville - Teeth Straightening, Invisalign & Dental Braces
- Orthodox Churches, Mooresville
- Orthopedic & Prosthetic Appliances & Shoes, Mooresville - Orthopedic Shoes
- Orthopedists, Mooresville - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Building Materials & Supplies, Mooresville
- Other Office Supply Stores, Mooresville
- Outboard Motors, Mooresville
- Outboard Motors Parts & Repair, Mooresville
- Outdoor & Lawn & Garden Equipment Repair & Service, Mooresville
- Outdoor Centers, Mooresville
- Outdoor Equipment & Accessories, Mooresville
- Outdoor Furniture, Mooresville
- Outdoor Power Equipment Repair, Mooresville
- Outpatient Services, Mooresville - Outpatient Care
- Ownership Organizations, Mooresville
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