- Obstetricians & Gynecologists, Reidsville - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Office Buildings & Parks, Reidsville
- Office Supplies, Equipment & Office Furniture Stores, Reidsville
- Oil & Gas Companies, Reidsville
- Oil & Petroleum Products, Reidsville - Merchant, Wholesalers, etc
- Oil Change & Lubrication, Reidsville - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Reidsville - Oil Companies
- Oil Petroleum Wholesale, Reidsville
- Oils Industrial, Reidsville
- Ophthalmologists, Reidsville - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optometrists, Reidsville - Eye Doctors, Physicians & Surgeons (Optometry)
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- Ornamental Greenhouses, Reidsville
- Ornamental Nursery, Reidsville
- Ornamental Nursery Services, Reidsville
- Orthodontist, Reidsville - Teeth Straightening, Invisalign & Dental Braces
- Orthopedists, Reidsville - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Building Materials & Supplies, Reidsville
- Outdoor Advertising & Billboard, Reidsville
- Outdoor Furniture & Patio Furniture, Reidsville - Garden Furniture Stores
- Outpatient Services, Reidsville - Outpatient Care
- Oxygen & Respiratory Equipment & Supplies, Reidsville - Oxygen Concentrator, Tank, Machine, etc
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