- Occupational Health Care Physicians & Surgeons, Roxboro - Occupational Medicine
- Occupational Health Care Professionals, Roxboro
- Office & Meeting Equipment & Supplies Rental, Roxboro
- Office Supplies, Equipment & Office Furniture Stores, Roxboro
- Oil & Gas Companies, Roxboro
- Oil And Petroleum Products, Roxboro
- Oil Change & Lubrication, Roxboro - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Roxboro - Oil Companies
- Oil Petroleum Wholesale, Roxboro
- Oncologists, Roxboro - Cancer Doctors, Physicians & Surgeons (Oncology)
- Ophthalmologists, Roxboro - Eye Doctors, Physicians & Surgeons (Ophthalmology)
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- Optical Stores - Eyeglasses, Lenses & Sunglasses, Roxboro
- Optometrists, Roxboro - Eye Doctors, Physicians & Surgeons (Optometry)
- Ornamental Nursery, Roxboro
- Ornamental Nursery Services, Roxboro
- Orthodontist, Roxboro - Teeth Straightening, Invisalign & Dental Braces
- Orthopedic & Prosthetic Appliances & Shoes, Roxboro - Orthopedic Shoes
- Orthopedists, Roxboro - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Building Materials & Supplies, Roxboro
- Other Office Supply Stores, Roxboro
- Outdoor Equipment & Accessories, Roxboro
- Outpatient Services, Roxboro - Outpatient Care
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