- Sand Gravel & Aggregate, Wadesboro
- Sandblasting, Wadesboro - General Contractors
- Sandwich Shop Restaurants, Wadesboro
- Satellite Descrambling & Programming Service, Wadesboro
- Satellite Dish Antennas & Equipment Dealers, Wadesboro
- Satellite TV Service, Wadesboro
- Savings Banks, Wadesboro
- Seafood Restaurants, Wadesboro
- Secondary Schools, Wadesboro
- Security & Surveillance System & Equipment, Wadesboro
- Security Guard & Patrol Service, Wadesboro - Bodyguard, Guard Dogs, Etc
- Security Services, Wadesboro
- Septic Tank Installation & Repair, Wadesboro - Septic Systems
- Septic Tank Pumping & Cleaning, Wadesboro - Septic Systems
- Septic Tanks & Septic Systems Contractors, Wadesboro - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Septic Tanks & Systems, Wadesboro - Wholesale, Dealers & Suppliers
- Sheriff's Department, Wadesboro
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- Shoe Stores, Wadesboro - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Wadesboro
- Signs, Wadesboro
- Social Clubs & Organizations, Wadesboro
- Social Services & Welfare, Wadesboro
- Societies & Foundation Associations, Wadesboro
- Specialty Communication Companies & Services, Wadesboro
- Specialty Stores, Wadesboro
- Sporting Goods Stores, Wadesboro
- Staffing & Support Services, Wadesboro
- State Government, Wadesboro
- Steel Manufacturers, Wadesboro
- Substance Abuse Clinics, Wadesboro - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Surveyor Services, Wadesboro - Surveying Service
- Surveyors, Wadesboro
- Swimming Pools Supplies, Equipment & Accessories, Wadesboro
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